Ophthalmology in China

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Clinical features of 39 patients with presumed tubercular retinal vasculitis

CAO Xu-sheng, LI Qian, HU Feng, PENG Xiao-yan   

  1. Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory Ophthalmology and Visual Science, Beijing Institute of Ophthalmology, Beijing 100730, China
  • Received:2019-09-03 Online:2019-09-25 Published:2019-09-24
  • Contact: PENG Xiao-yan, Email: drpengxy@163.com

Abstract:

Objective To investigate the clinical features of presumed tubercular retinal vasculitis. Design Retrospective case series. Participants 39 consecutive patients (72 eyes) with presumed tubercular retinal vasculitis who consulted at the ophthalmic clinic of Beijing Tongren Hospital from June 2013 to June 2019. Methods We retrospectively reviewed the clinical features of the above-mentioned 39 patients (72 eyes). Main Outcome Measures Age, sex, systemic tuberculosis history, causes of visual impairment, laterality, the features of color fundus photography, fundus fluorescein angiography (FFA) and optical coherence tomography (OCT). Results Mean age of the enrolled patients was 32.3±12.3 years. The patients were predominantly male (n=33/39; 84.6%). 7 patients (17.9%) had known history of systemic tuberculosis. A total of 33 patients (84.6%) had bilateral involvement. 29 patients (38 eyes) consulted at the clinic because of vitreous hemorrhage, 4 patients (5 eyes) of them had underwent pars plana vitrectomy and/or silicon oil injection. Among the 62 eyes which can be distinguished by color fundus photography and FFA, 54 eyes (87.1%) had occlusive type retinal vasculitis and/ or retinal neovascularization, 22 eyes (35.5%) had macular edema, 15 eyes (24.2%) had active or healed focal choroiditis lesions, 9 eyes (14.5%) had secondary branch retinal venous occlusion. Conclusions Male, bilateral involvement, vitreous hemorrhage, occlusive retinal vasculitis and/ or secondary retinal neovascularization, macular edema, focal choroiditis lesions, and secondary branch retinal venous occlusion are common clinical features of presumed tubercular retinal vasculitis. (Ophthalmol CHN, 2019, 28: 341-344)

Key words: retinal vasculitis, tuberculosis, tuberculous uveitis